Overview. Hydroxytyrosol (3,4-Dihydroxyphenylethanol, C8H10O3) is a catechol-type phenolic compound found in olive leaves, olives, and extra virgin olive oil, and the molecule behind the Mediterranean diet's celebrated health benefits. Due to its ortho-dihydroxy (catechol) structure, hydroxytyrosol exhibits radical-scavenging potency that significantly exceeds vitamin C, vitamin E, and coenzyme Q10 on a molar basis. YaoSynBio offers hydroxytyrosol as off-white crystals or a golden-yellow viscous liquid, produced through a green biotechnology synthesis route from olive-derived feedstocks for high purity, low environmental impact, and reliable supply.
Mechanism of Action. Hydroxytyrosol's catechol group donates hydrogen atoms to quench free radicals across multiple reactive species, giving it one of the highest ORAC (oxygen radical absorbance capacity) values of any natural molecule. It upregulates the Nrf2 antioxidant response pathway, boosting the skin's own endogenous defense enzymes (such as SOD and glutathione), while downregulating NF-κB-driven inflammatory cascades to reduce redness and irritation. It inhibits lipid peroxidation in cell membranes, protects against UV-induced oxidative damage and photoaging, and — as documented in EFSA-recognized olive polyphenol health claims — supports cardiovascular health by protecting LDL particles from oxidation. In skin, this translates to reduced oxidative aging, calmed stressed skin, and reinforced environmental protection.
Applications. Hydroxytyrosol is suited to antioxidant serums, anti-pollution and anti-aging creams, soothing treatments, after-sun care, and nutricosmetic/beauty-from-within formulations. Its dual food-and-cosmetic compliance and EFSA-endorsed health-claim heritage make it a compelling active for “edible-grade skincare” and ingestible beauty concepts, as well as functional foods and beverages. Regulatory status: EFSA-approved health claims for olive polyphenols in the EU and compliance with EC 1223/2009 for cosmetics; FDA GRAS status in the US..
| INCI Name | Hydroxytyrosol (3,4-Dihydroxyphenylethanol) |
|---|---|
| CAS No. | 10597-60-1 |
| Molecular Formula | C8H10O3 |
| Appearance | Off-white crystals or yellow viscous liquid |
| Purity | High-purity polyphenol grade |
| Recommended Dosage | 0.1% – 1% (cosmetic) |
| Storage | Store sealed under inert atmosphere, cool and dark; protect from oxidation; 2–8 °C recommended for liquid form |
| Source | Natural polyphenol from olive leaves and fruits; green biotech synthesis |
| Key Benefits |
